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G protein-coupled receptor 34
Symbols GPR34 ; LYPSR1
External IDs OMIM300241 MGI1346334 HomoloGene36174 IUPHAR: 101 GeneCards: GPR34 Gene
Species Human Mouse
Entrez 2857 23890
Ensembl ENSG00000171659 ENSMUSG00000040229
UniProt Q9UPC5 Q9R1K6
RefSeq (mRNA) NM_001033513 NM_011823
RefSeq (protein) NP_001091048 NP_035953
Location (UCSC) Chr X:
41.69 – 41.7 Mb
Chr X:
13.63 – 13.64 Mb
PubMed search [1] [2]

Probable G-protein coupled receptor 34 is a protein that in humans is encoded by the GPR34 gene.[1][2][3]

G protein-coupled receptors (GPCRs), such as GPR34, are integral membrane proteins containing 7 putative transmembrane domains (TMs). These proteins mediate signals to the interior of the cell via activation of heterotrimeric G proteins that in turn activate various effector proteins, ultimately resulting in a physiologic response.[supplied by OMIM][3]


  1. ^ Schoneberg T, Schulz A, Grosse R, Schade R, Henklein P, Schultz G, Gudermann T (Aug 1999). "A novel subgroup of class I G-protein-coupled receptors". Biochim Biophys Acta 1446 (1–2): 57–70. doi:10.1016/s0167-4781(99)00081-0. PMID 10395919. 
  2. ^ Marchese A, Sawzdargo M, Nguyen T, Cheng R, Heng HH, Nowak T, Im DS, Lynch KR, George SR, O'dowd BF (May 1999). "Discovery of three novel orphan G-protein-coupled receptors". Genomics 56 (1): 12–21. doi:10.1006/geno.1998.5655. PMID 10036181. 
  3. ^ a b "Entrez Gene: GPR34 G protein-coupled receptor 34". 

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