Probable G-protein coupled receptor 61 is a protein that in humans is encoded by the GPR61gene.
This gene belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. The protein encoded by this gene is most closely related to biogenic amine receptors.
^Lee DK, George SR, Cheng R, Nguyen T, Liu Y, Brown M, Lynch KR, O'Dowd BF (Feb 2001). "Identification of four novel human G protein-coupled receptors expressed in the brain". Brain Res Mol Brain Res86 (1–2): 13–22. doi:10.1016/S0169-328X(00)00242-4. PMID11165367.
^Cikos S, Gregor P, Koppel J (Nov 2001). "Cloning of a novel biogenic amine receptor-like G protein-coupled receptor expressed in human brain". Biochim Biophys Acta1521 (1–3): 66–72. doi:10.1016/s0167-4781(01)00289-5. PMID11690637.
Conner AC, Hay DL, Simms J, et al. (2005). "A key role for transmembrane prolines in calcitonin receptor-like receptor agonist binding and signalling: implications for family B G-protein-coupled receptors". Mol. Pharmacol.67 (1): 20–31. doi:10.1124/mol.67.1. PMID15615699.