GREB1

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GREB1
Identifiers
AliasesGREB1, growth regulation by estrogen in breast cancer 1, growth regulating estrogen receptor binding 1
External IDsMGI: 2149712 HomoloGene: 8780 GeneCards: GREB1
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for GREB1
Genomic location for GREB1
Band2p25.1Start11,482,341 bp[1]
End11,642,788 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014668
NM_033090
NM_148903

NM_001252071
NM_015764

RefSeq (protein)

NP_055483
NP_149081
NP_683701

NP_001239000
NP_056579

Location (UCSC)Chr 2: 11.48 – 11.64 MbChr 12: 16.67 – 16.8 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Growth regulation by estrogen in breast cancer 1 is a protein that in humans is encoded by the GREB1 gene.[5]

Function[edit]

This gene is an estrogen-responsive gene that is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and cancer. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[5]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000196208 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000036523 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ a b "Entrez Gene: Growth regulation by estrogen in breast cancer 1".

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.