GRIP1 (gene)

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Protein GRIP1 PDB 1m5z.png
Available structures
PDB Ortholog search: PDBe RCSB
Aliases GRIP1, GRIP, glutamate receptor interacting protein 1
External IDs MGI: 1921303 HomoloGene: 12938 GeneCards: 23426
RNA expression pattern
PBB GE GRIP1 214018 at tn.png
More reference expression data
Species Human Mouse
RefSeq (mRNA)


RefSeq (protein)


Location (UCSC) Chr 12: 66.35 – 66.8 Mb Chr 10: 119.45 – 120.09 Mb
PubMed search [1] [2]
View/Edit Human View/Edit Mouse

Glutamate receptor-interacting protein 1 is a protein that in humans is encoded by the GRIP1 gene.[3][4]


GRIP1 (gene) has been shown to interact with:


  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Bruckner K, Pablo Labrador J, Scheiffele P, Herb A, Seeburg PH, Klein R (April 1999). "EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains". Neuron. 22 (3): 511–24. doi:10.1016/S0896-6273(00)80706-0. PMID 10197531. 
  4. ^ "Entrez Gene: GRIP1 glutamate receptor interacting protein 1". 
  5. ^ a b c d e Hirbec H, Perestenko O, Nishimune A, Meyer G, Nakanishi S, Henley JM, Dev KK (May 2002). "The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs". J. Biol. Chem. 277 (18): 15221–4. doi:10.1074/jbc.C200112200. PMID 11891216. 
  6. ^ Hirbec H, Francis JC, Lauri SE, Braithwaite SP, Coussen F, Mulle C, Dev KK, Coutinho V, Meyer G, Isaac JT, Collingridge GL, Henley JM, Couthino V (February 2003). "Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP". Neuron. 37 (4): 625–38. doi:10.1016/S0896-6273(02)01191-1. PMC 3314502free to read. PMID 12597860. 
  7. ^ Ye B, Liao D, Zhang X, Zhang P, Dong H, Huganir RL (June 2000). "GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex". Neuron. 26 (3): 603–17. doi:10.1016/S0896-6273(00)81198-8. PMID 10896157. 

Further reading[edit]