GRWD1

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GRWD1
Identifiers
AliasesGRWD1, CDW4, GRWD, RRB1, WDR28, glutamate-rich WD repeat containing 1, glutamate rich WD repeat containing 1
External IDsOMIM: 610597 MGI: 2141989 HomoloGene: 6644 GeneCards: GRWD1
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_031485

NM_153419

RefSeq (protein)

NP_113673

NP_700468

Location (UCSC)Chr 19: 48.45 – 48.46 MbChr 7: 45.47 – 45.48 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Glutamate-rich WD repeat-containing protein 1 is a WD40 repeat protein that in humans is encoded by the GRWD1 gene. It localizes to the nucleus and has known functions in regulating chromatin openness and loading of MCM helicase.[5][6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000105447 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000053801 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Gratenstein K, Heggestad AD, Fortun J, Notterpek L, Pestov DG, Fletcher BS (Jun 2005). "The WD-repeat protein GRWD1: potential roles in myeloid differentiation and ribosome biogenesis". Genomics. 85 (6): 762–73. doi:10.1016/j.ygeno.2005.02.010. PMID 15885502.
  6. ^ "Entrez Gene: GRWD1 glutamate-rich WD repeat containing 1".

Further reading[edit]