Pendetide

From Wikipedia, the free encyclopedia
  (Redirected from GYK-DTPA)
Jump to: navigation, search
Pendetide
Pendetide structure.svg
Names
IUPAC name
N6-[N-[2-[[2-[Bis(carboxymethyl)amino]ethyl](carboxymethyl)amino]ethyl]-N-(carboxymethyl)glycyl]-N2-(N-glycyl-L-tyrosyl)-L-lysine
Identifiers
3D model (JSmol)
ChemSpider
Properties
C31H47N7O14
Molar mass 741.318 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Pendetide (GYK-DTPA) is a chelating agent. It consists of pentetic acid (DTPA) linked to the tripeptide glycine (G) – L-tyrosine (Y) – L-lysine (K).[1]

Use[edit]

The following monoclonal antibodies are linked to pendetide to chelate a radionuclide, indium-111. The antibodies selectively bind to certain tumour cells, and the radioactivity is then used for imaging of the tumours.

References[edit]