Souart entered the priesthood later in life, having previously studied and practiced medicine. He became a priest in 1650 and was sent to New France to help found the Séminaire de Montréal. At the same time he began to organize the parish which had previously been ministered to by the Jesuits as a group since 1642. He also acted as an able replacement for his superior, Abbé Queylus, chaplain of the Notre-Dame congregation and Hôtel-Dieu de Montréal.
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