Gaines may refer to:
- United States
- Gaines, Michigan, a village
- Gaines Township, Genesee County, Michigan, a civil township in which the above village is located
- Gaines Township, Kent County, Michigan, a charter township
- Gaines, Missouri, an unincorporated community
- Gaines, New York, a town
- Gaines, West Virginia, an unincorporated community
|This disambiguation page lists articles associated with the title Gaines.
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