Gandy–Gamna nodules

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Gandy–Gamna nodules or Gandy-Gamna bodies, sometimes known as Gamna-Gandy bodies or Gamna-Gandy nodules, are small yellow-brown, brown, or rust-colored foci found in the spleen in patients with splenomegaly due to portal hypertension,[1] as well as sickle cell disease. They consist of fibrous tissue with haemosiderin and calcium deposits, and probably form due to scarring at sites of small perivascular haemorrhages.[2] They are visible on MRI scanning due to the presence of haemosiderin.[3]

They can also be seen in atrial myxomas.

They are named after Charles Gandy and Carlos Gamna.

External links[edit]

Gandy-Gamna bodies at Who Named It?


  1. ^ Kuntz, Erwin; Kuntz, Hans-Dieter (11 March 2009). Hepatology: Textbook and Atlas. Springer Science & Business Media. p. 253. ISBN 9783540768395. Prolonged portal hypertention sometimes leads to the formation of Gamna-Gandy nodules.
  2. ^ Gandy-Gamna bodies at Mondofacto online medical dictionary
  3. ^ Gamna Gandy bodies in the spleen evaluated on MRI