She is a co-founder of the Druid Theatre Company with Mick Lally and Marie Mullen in 1975 after meeting through the drama society of NUI Galway where they studied. She was Druid's artistic director from 1975 to 1991, and again from 1995 to date. Hynes directed for the Abbey Theatre from 1984 and was its artistic director from 1991 to 1994, and also the Royal Shakespeare Company, the Royal Exchange, Manchester, the Kennedy Center and the Royal Court Theatre, London.
She is the civil partner of film producer Martha O'Neill.
Hynes directed DruidSynge, the company’s critically acclaimed production of all six of John Millington Synge’s plays that premièred at the Galway Arts Festival in 2005 and has since toured to Dublin, Edinburgh, Inis Meáin, Minneapolis and New York. DruidSynge has been described by Charles Isherwood of The New York Times as "the highlight not just of my theatre going year but of my theatre going life" and by The Irish Times as "one of the greatest achievements in the history of Irish theatre."
Awards and honours
She is a recipient of many other Theatre Awards, including The Irish Times/ESB Irish Theatre Award for Best Director (2002) and a The Irish Times Special Tribute Award for her contribution to Irish Theatre in February 2005.
- Eidhean mac Cléireach - ancestor of the Hynes family
- Mael Ruanaidh na Paidre Ua hEidhin - first Hynes king of Aidhne
- Eoghan Ó hEidhin - last Hynes king of Aidhne
- Uí Fiachrach Aidhne - home kingdom of the Hynes family
- Fay, Stephen. "theatre: How she broke the Abbey habit" Independent, 5 September 1992
- Siggins, Lorna (19 December 2014). "Druid artistic director Garry Hynes and producer Martha O'Neill become civil partners: Private ceremony took place in Druid's Mick Lally Theatre". The Irish Times.
- Bacalzo, Dan. "Full Cast Announced for Encores! 'Juno'" theatermania.com, 4 March 2008
- " Translations McCarter Theatre" mccarter.org, accessed 7 April 2016
- Gutman, Les."Review. 'Crimes of the Heart' curtainup.com, 2001, accessed 7 April 2016
- Fricker, Karen. "Review. 'Crestfall'" The Guardian, 23 May 2003
- 16 Wounded ibdb.com, accessed 7 April 2016
- Marks, Peters. "Uneven 'Streetcar' Still Something To Be Desired" The Washington Post, 15 May 2004
- Isherwood, Charles. "Review" The New York Times, 12 July 2006
-  druidsynge.com
- McGee, Celia. "Garry Hynes, an Irish Director, Arrives With 8½ Hours of Her Countryman" The New York Times, 2 July 2006
- Lefkowitz, David; Viagas, Robert. "RRRROOAARRRR!!! It's 'The Lion King' for Best Musical; 'Art' for Play Tonys" Playbill, 7 June 1998
- McGarry, Patsy. "'Distinctive and powerful record' of Garry Hynes' work recognised" Irish Times, 15 February 2005
- "Freedom of the City for Garry Hynes Saoirse na Cathrach do Ghearóidín Ní Eidhin". Galway City Council. 16 June 2006. Retrieved 2008-05-28.