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The Gashadokuro are spirits that take the form of giant skeletons and are fifteen times taller than an average person, said to be created from the amassed bones of people who died of starvation. These Yōkai roam after midnight, grabbing lone travelers and biting off their heads to drink their spraying blood. There is a tell sign as the victim would hear the sound of loud ringing in the ear. The Gashadokuro are said to possess the powers of invisibility and indestructibility; though Shinto charms are said to ward them off.
In AdventureQuest Worlds, the Gashadokuro is featured as the forbidden Beast of Chaos called the O-Dokuro. Kitsune uses the Hanzamune Blade to free it from a time rift and bring it to Yokai Island. Later on, the players can fight a monster called O'Dokuro's Head.
In Yo-kai Watch, there is a Yo-kai called Gutsy Bones but it is a reference to gashapons which are toys from Japan you try to get from coin machines like gumballs.
In Okamiden, there is a demon known as a Gashadokuro which resembles a humongous human skeleton with a fiery core and twin blades embedded in its stomach. There is also an armoured version which is much more powerful.
In the manga/anime series, Inu x Boku SS, Roromiya Karuta is a Gashadokuro.