Gene Designer

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Gene Designer
Gene Designer Sequence View enables manipulation of sequence elements, codon choices, and oligonucleotide positions. Rapidly search for sequence motifs, restriction sites, and open reading frames.
Gene Designer Sequence View enables manipulation of sequence elements, codon choices, and oligonucleotide positions. Rapidly search for sequence motifs, restriction sites, and open reading frames.
Developer(s) DNA2.0[1]
Initial release 2006; 11 years ago (2006)
Stable release
2.01.191 / October 9, 2015; 22 months ago (2015-10-09)
Development status Active
Operating system Windows, macOS, Linux
Platform x86, x86-64
Available in English
Type Molecular biology toolkit
License Freeware, registration required
Website www.dna20.com/resources/genedesigner

Gene Designer is a computer software package for bioinformatics.[2][3] It is used by molecular biologists from academia, government, and the pharmaceutical, chemical, agricultural, and biotechnology industries to design,[4] clone, and validate genetic sequences. It is proprietary software, released as freeware needing registration.

Features[edit]

Gene Designer enables molecular biologists to manage the full gene design process in one application, using a range of design tools.

Gene Designer clones with a drag and drop feature. Users can drag a vector and insert into the Cloning Tool; cut, combine and clone. Gene Designer assembles a clone that can then be dropped directly into a project.

Educator and student use[edit]

This free software has been incorporated into classroom and lab curricula for synthetic biology, systems biology, bioengineering, and bioinformatics. Students create and complete projects which manage the full gene design process in one application, using a range of design tools.

Examples of use in curricula:

See also[edit]

References[edit]

  1. ^ DNA2.0
  2. ^ Villalobos, Alan; Ness, Jon E; Gustafsson, Claes; Minshull, Jeremy; Govindarajan, Sridhar (2006). "Gene Designer: A synthetic biology tool for constructing artificial DNA segments". BMC Bioinformatics. 7: 285. PMC 1523223Freely accessible. PMID 16756672. doi:10.1186/1471-2105-7-285. 
  3. ^ Villalobos, Alan; Welch, Mark; Minshull, Jeremy (2012). "Gene Synthesis". Methods in molecular biology (Clifton, N.J.). Methods in Molecular Biology. 852: 197–213. ISBN 978-1-61779-563-3. PMID 22328435. doi:10.1007/978-1-61779-564-0_15.  |chapter= ignored (help)
  4. ^ Welch, M; Villalobos, A; Gustafsson, C; Minshull, J (2011). "Designing genes for successful protein expression". Methods in enzymology. Methods in Enzymology. 498: 43–66. ISBN 9780123851208. PMID 21601673. doi:10.1016/B978-0-12-385120-8.00003-6. 

External links[edit]

Tutorials

Other software[edit]