Gene transfer agent-release holin family

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Gene transfer agent-release holins (GTA-Hol, TC# 1.E.54) are holins which are believed to facilitate the lysis-dependent release of a gene transfer agent. Particularly the gene transfer agent of Rhodobacter capsulatus (RcGTA), which is known to be a bacteriophage-like genetic element that induces horizontal gene transfer. The promoter of the RcGTA gene was identified by Westbye et al. in 2013.[1] A representative list of members belonging to the GTA-Hol family can be found in the Transporter Classification Database with homologues found in proteobacteria and caudovirales.[1][2]

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  1. ^ a b Westbye, A. B.; Leung, M. M.; Florizone, S. M.; Taylor, T. A.; Johnson, J. A.; Fogg, P. C.; Beatty, J. T. (2013-11-01). "Phosphate concentration and the putative sensor kinase protein CckA modulate cell lysis and release of the Rhodobacter capsulatus gene transfer agent". Journal of Bacteriology. 195 (22): 5025–5040. doi:10.1128/JB.00669-13. ISSN 1098-5530. PMC 3811591Freely accessible. PMID 23995641. 
  2. ^ "1.E.54 The Gene Transfer Agent-release Holin (GTA-Hol) Family". TCDB. Retrieved 2016-03-29. 

Further reading[edit]

As of 2016-03-29, this article is derived in whole or in part from the Transporter Classification Database. The copyright holder has licensed the content in a manner that permits reuse under CC BY-SA 3.0 and GFDL. All relevant terms must be followed. The original text was at "1.E.54. The Gene Transfer Agent-release Holin (GTA-Hol) Family".