Genetic studies on Sinhalese
All studies agree that there is a significant relationship between the Sinhalese and the South Indian Tamils and Bengalis and that there is a significant genetic relationship between Sri Lankan Tamils and Sinhalese, them being closer to each other than other South Asian populations. This is also supported by a genetic distance study, which showed low differences in genetic distance between the Sinhalese and the Tamil, Keralite and Bengali volunteers.
A 2017 study conducted by Fumihiko Takeuchi, Tomohiro Katsuya, Ryosuke Kimura and Norihiro Kato showed that the main ancestral population that contributed to the Sinhalese was the "South Asian" component with a significant contribution from the "South Asian and Central Asian" component and smaller contributions from the "Central Asian", "Southeast Asian", "Southeast Asian and East Asian", "East Asian" and "Japanese" components.
Relationship to Bengalis
An Alu polymorphism analysis of Sinhalese from Colombo by Dr Sarabjit Mastanain in 2007 using Tamil, Bengali, Gujarati (Patel), and Punjabi as parental populations found different proportions of genetic contribution:
|Statistical Method||Bengali||Tamil||North Western|
|Maximum Likelihood Method||88.07%||-||-|
|Using Tamil, Bengali and North West as parenteral population||50-66%||11-30%||20-23%|
|Using Tamil and Bengali as parenteral population||70.03%||29.97%||-|
|Using Tamil, Bengali and Gujarati as parenteral population||71.82%||16.38%||11.82%|
|Using Bengali, Gujarati and Punjabi as parenteral population||82.09%||-||15.39%||2.52%|
D1S80 allele frequency (A popular allele for genetic fingerprinting) is also similar between the Sinhalese and Bengalis, suggesting the two groups are closely related. The Sinhalese also have similar frequencies of the allele MTHFR 677T (13%) to West Bengalis (17%).
A test for Y-chromosome DNA haplogroups conducted by Dr Toomas Kivisild on Sinhalese of Sri Lanka has shown that 23% of the subjects were R1a1a (R-SRY1532) positive. Also in the same test 24.1% of the subjects were R2 positive as subclades of Haplogroup P (92R7). Haplogroup R2 is also found in a considerable percentage among Bengali of India. Sample size used was 87 subjects.
A study in 2007 found similar frequencies of the allele HLA-A*02 in sinhalese (7.4%) and North Indian subjects (6.7%). HLA-A*02 is a rare allele which has a relatively high frequency in North Indian populations and is considered to be a novel allele among the North Indian population. This suggests possible North Indian origin of the Sinhalese.
Relationship to other ethnic groups in Sri Lanka
A study looking at genetic variation of the FUT2 gene in the Sinhalese and Sri Lankan Tamil population, found similar genetic backgrounds for both ethnic groups, with little genetic flow from other neighbouring Asian population groups. Studies have also found no significant difference with regards to blood group, blood genetic markers and single-nucleotide polymorphism between the Sinhalese and other ethnic groups in Sri Lanka. Another study has also found "no significant genetic variation among the major ethnic groups in Sri Lanka". This is further supported by a study which found very similar frequencies of alleles MTHFR 677T, F2 20210A & F5 1691A in South Indian Tamil, Sinhalese, Sri Lankan Tamil and Moor populations.
Relationship to East and Southeast Asians
Genetic studies show that the Sinhalese have received some genetic flow from neighboring populations in East Asia and Southeast Asia, such as from the ethnically diverse and disparate Tibeto-Burman peoples and Austro-Asiatic peoples, which is due to their close genetic links to Northeast India. A 1985 study conducted by Roychoudhury AK and Nei M, indicated the values of genetic distance showed that the Sinhalese people were slightly closer to Mongoloid populations due to gene exchange in the past. In regards to comparisons of root and canal morphology of Sri Lankan mandibular molars, it showed that they were further away from Mongoloid populations. Among haplogroups found in East Asian populations, a lower frequency of East Asian mtDNA haplogroup, G has been found among the populations of Sri Lanka alongside haplogroup D in conjunction with the main mtDNA haplogroup of Sri Lanka's ethnic groups, haplogroup M. In regards to Y-DNA, Haplogroup C-M130 is found at low to moderate frequencies in Sri Lanka.
Genetic markers of immunoglobulin among the Sinhalese show high frequencies of afb1b3 which has its origins in the Yunnan and Guangxi provinces of southern China. It is also found at high frequencies among Odias, certain Nepali and Northeast Indian, southern Han Chinese, Southeast Asian and certain Austronesian populations of the Pacific Islands. At a lower frequency, ab3st is also found among the Sinhalese and is generally found at higher frequencies among northern Han Chinese, Tibetan, Mongolian, Korean and Japanese populations. The Transferrin TF*Dchi allele which is common among East Asian and Native American populations is also found among the Sinhalese. HumDN1*4 and HumDN1*5 are the predominant DNase I genes among the Sinhalese and are also the predominant genes among southern Chinese ethnic groups and the Tamang people of Nepal. A 1988 study conducted by N. Saha, showed the high GC*1F and low GC*1S frequencies among the Sinhalese are comparable to those of the Chinese, Japanese, Koreans, Thais, Malays, Vietnamese, Laotians and Tibetans. A 1998 study conducted by D.E. Hawkey showed dental morphology of the Sinhalese is closely related to those of the Austro-Asiatic populations of East and Northeast India. Hemoglobin E a variant of normal hemoglobin, which originated in and is prevalent among populations in Southeast Asia, is also common among the Sinhalese and can reach up to 40% in Sri Lanka.
In 2008 a study looked at SLC24A5 polymorphism which accounts for 25-40% of the skin complexion difference between Europeans and Africans and up to 30% of skin colour variation in South Asians. The study found that the rs1426654 SNP of SLC24A5, which is fixed in European populations and found more commonly in light skinned individuals than dark skinned individuals (49% compared to 10%), has a frequency of 50-55% in the Sinhalese and 25-30% in Sri Lankan Tamils. This allele could have arisen in the Sinhalese due to strong East Asian genetic admixture, further migration from North India or strong selection factors.
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