Georg Ledderhose

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Georg Ledderhose

Georg Ledderhose (15 December 1855, Bockenheim, Regierungsbezirk Wiesbaden, Germany – 1 February 1925, Munich, Germany) was a German surgeon.[1]

Ledderhose studied in Strasbourg[2] under Georg Albert Lücke (1829–1894),[1] receiving his medical doctorate in 1880 and later working in Strasbourg hospital as a surgeon.[1] He became Professor for Surgery in Strasbourg in 1891.[2] He later worked in Munich, where he became honorary professor.[1]

In 1876, Ledderhose discovered glycosamine whilst working on cartilage with Ernst Felix Immanuel Hoppe-Seyler (1825–1895) in Strassburg.[3][4] Although first identified by him, the stereochemistry of the compound was not fully defined until 1939 by the work of Walter Haworth.[5][6]

Ledderhose was the first to describe the condition of plantar fibromatosis in 1894,[7][8] which was later known as Ledderhose's disease.


  1. ^ a b c d "Georg Ledderhose (". Retrieved 2007-12-28.
  2. ^ a b "Georg Ledderhose". Retrieved 2007-12-28.
  3. ^ Georg Ledderhose (1876) "Über salzsaures Glycosamin" [On glucosamine hydrochloride], Berichte der deutschen chemischen Gesellschaft, 9(2): 1200-1201.
  4. ^ Joseph S. Fruton (1990). Contrasts in Scientific Style: Research Groups in the Chemical and Biochemical Sciences. DIANE. p. 313. ISBN 0-87169-191-4.
  5. ^ W. N. Haworth, W. H. G. Lake, and S. Peat (1939) "The configuration of glucosamine (chitosamine)," Journal of the Chemical Society, pages 271-274.
  6. ^ Horton, Derek; Wander, J.D. (1980). The Carbohydrates Vol IB. New York: Academic Press. pp. 727–728. ISBN 0-12-556351-5.
  7. ^ Ledderhose G (1894). "Ueber Zerreisungen der Plantarfascie (On tears in the plantar fascia)". Archiv für Klinische Chirurgie. 48: 853–856.
  8. ^ "Dupuytren's contracture - Patient UK". Retrieved 2007-12-28.