Broussard released his early games under the name Micro F/X. In 1991, Broussard partnered with Scott Miller as co-owner of Apogee Software and 3D Realms. Broussard is perhaps best known for his 12+ year development with many hurdles of Duke Nukem Forever, before he asked Gearbox Software to take over, which ultimately finished the project. The 3D Realms website notes that he is probably the only person in the industry to have misspelled his own name (as "Broussad") on a shareware title he created on his own, Pharaoh's Tomb.
In 2013, Broussard competed in the indie game competition Ludum Dare with The Road, a side-scrolling browser game that reflects on the futility of existence.
Broussard suffered a minor stroke in May 2014 and recovered quickly.