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Mateljan is a founder of Health Valley Foods. After selling the company, he established a not-for-profit foundation The George Mateljan Foundation for the World's Healthiest Foods to provide an accessible reference for people looking for good tasting, convenient ways to eat and prepare foods healthfully.
Mateljan wrote several nutrition books, including: Cooking Without Fat, Baking Without Fat, Healthier Living Cuisine, Healthier Eating Guide, and Natural Foods Cookbook.