Salis-Schwabe was the son of Salis (born Salomon ben Elias; 1800–1853) Schwabe of Crumpsall House, Manchester and Glyn Garth, Anglesey, formerly of Rhodes House, Middleton, a successful cotton printer of Westphalian Jewish origin who had settled in England in 1817 and converted to the Unitarian church, and his wife, noted educationalist Julie Schwabe (her husband's cousin). His parents had a wide circle of notable friends. He was educated at University College School, London and London University . He joined the army and became Lieutenant-Colonel commanding the 16th Lancers. He was Brigade Major of Cavalry at the Curragh and at Aldershot from 1873 to 1877. He served in the Anglo-Zulu War in 1879 when he was mentioned in despatches and awarded Medal with Clasp. He was a partner in firm of Salis Schwabe & Co, Calico Printers, of Rhodes and Manchester.
At the 1885 general election Salis-Schwabe was elected as the Member of Parliament (MP) for the new Middleton division of Lancashire. When the Liberals split over Home Rule for Ireland, he joined the breakaway Liberal Unionist Party, and did not stand again at the 1886 election.
George Salis Schwabe was Lieutenant Governor of the Chelsea Royal Hospital from 1898 to 1903. He was appointed a Companion of the Order of the Bath (CB) in the 1902 Coronation Honours list published on 26 June 1902, and received the decoration from King Edward VII at Buckingham Palace on 24 October 1902.
He died on 13 July 1907, at the age of 63.
Salis-Schwabe married in 1870 Mary Jaqueline James, daughter of Sir William Milbourne James, Lord Justice of Appeal. They had five children: Maurice Salis Schwabe (born 1871 in Easthampstead, Berkshire), Sir Walter George Salis Schwabe (born 1873), K.C., sometime Chief Justice of the Madras High Court, Edgar William Salis Schwabe (born 1875 in Ireland), Gladys Mary Salis Schwabe (Born in Prestwich 11 March 1878) and Rhoda Jaqueline Salis Schwabe (born in Ireland 1885). Gladys married British businessman Paul Crompton and died with him and their six children in the 7 May 1915 sinking of the RMS Lusitania.
- Leigh Rayment's Historical List of MPs – Constituencies beginning with "M" (part 2)
- Mair, Robert Henry (1886). Debrett's Illustrated House of Commons and the Judicial Bench 1886. London: Dean & Son. p. 135.
- Fryderyk Chopin- A Life and Times, Alan Walker, Farrar, Strauss and Giroux
- New Illustrated Lives of Great Composers: Chopin, Ates Orga, Omnibus Press, 2015
- Musical Visitors to Britain, Peter Gordon, 2007, p. 155
- Patrick Waddington, ‘Schwabe, Julie (1818–1896)’, Oxford Dictionary of National Biography, Oxford University Press, 2004; online edn, Oct 2006 accessed 4 Sept 2015
- Salis and Julie Schwabe
- "No. 25541". The London Gazette. 18 December 1885. p. 6135.
- Craig, F. W. S. (1989) . British parliamentary election results 1885–1918 (2nd ed.). Chichester: Parliamentary Research Services. p. 322. ISBN 0-900178-27-2.
- "The Coronation Honours". The Times (36804). London. 26 June 1902. p. 5.
- "No. 27448". The London Gazette (Supplement). 26 June 1902. p. 4190.
- "Court Circular". The Times (36908). London. 25 October 1902. p. 8.
- Debrett's Baronetage, Knightage and Companionage, 1931, pg 1221
- Hansard 1803–2005: contributions in Parliament by George Salis-Schwabe
|Parliament of the United Kingdom|
|| Member of Parliament for Middleton
Andrew Smythe Montague Browne
| Colonel of the 3rd (Prince of Wales's) Dragoon Guards
Sir Reginald Talbot