SR 82 begins at an intersection with SR 11/SR 53/SR 211 in Winder. The route heads east from Winder to a second intersection with SR 211, northeast of Statham. Just east of that intersection, SR 82 intersects SR 330. A little ways to the northeast, the route enters Jackson County.
In the city of Arcade, SR 82 intersects US 129/SR 11 Conn. Just to the northeast, the highway intersects US 129 Bus./SR 15 Alt. The three highways begin a concurrency northwest to Jefferson. In the city, they intersect SR 11 Bus. SR 11 Bus. joins the concurrency for just two blocks. At this intersection, US 129 Bus./SR 11 Bus. depart to the northwest, while SR 15 Alt./SR 82 travel to the northeast. Just before leaving the city, the two routes split, with SR 82 heading to the north. Northwest of Jackson County Airport, the route intersects SR 82 Conn. Farther to the northwest, Interstate 85 (I-85) crosses the path.
State Route 82 Connector (SR 82 Conn.) is a 4.7-mile-long (7.6 km) connector route that begins at an intersection with the SR 82 mainline (Dry Pond Road), north of Jefferson. It travels to the east-northeast, and curves to the north-northwest. It crosses over, but does not have an interchange with, Interstate 85 (I-85) approximately 2 miles (3.2 km) later. It curves to the northeast and skirts along the northwestern edge of Hurricane Shoals County Park. It crosses over the North Oconee River and curves back to the north-northwest. The route passes Riverside Cemetery and then enters Maysville. It curves to the north-northeast and passes Maysville Elementary School before it meets its northern terminus, an intersection with SR 98 (Maysville Road).