She received a B.S. University of Maine, Orono in 1986, graduated from Princeton University with a Ph.D. in 1991, and did post-doctoral training at the Carnegie Institution. Her work focused on the earliest stages of embryogenesis and how single-celled eggs develop into multicellular embryos. It focuses on how embryos choose between soma and germline. The Seydoux lab’s goal is to ascertain the process in which embryonic development and polarization is activated using Caenorhabditis elegans. She has also validated that proteins in a fertilizing sperm trigger the reorganization of structural proteins inside the ovum. This is an essential step in forming the anterior-posterior polarization of the one celled embryo. Geraldine Seydoux’s studies provide much insight into the creation of a fully formed multicellular organism from a single cell. She was elected to the National Academy of Sciences in 2016.
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