Geraniol 8-hydroxylase
| Geraniol 8-hydroxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.13.152 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Geraniol 8-hydroxylase (EC 1.14.13.152, CYP76B6, G10H, CrG10H, SmG10H) is an enzyme with systematic name geraniol,NADPH:oxygen oxidoreductase (8-hydroxylating).[1][2][3] This enzyme catalyses the following chemical reaction
- geraniol + NADPH + H+ + O2 (6E)-8-hydroxygeraniol + NADP+ + H2O
Geraniol 8-hydroxylase is a cytochrome P450 and therefore requires a partner cytochrome P450 reductase for functional expression.
References
- ^ Collu, G., Unver, N., Peltenburg-Looman, A.M., van der Heijden, R., Verpoorte, R. and Memelink, J. (2001). "Geraniol 10-hydroxylase, a cytochrome P450 enzyme involved in terpenoid indole alkaloid biosynthesis". FEBS Lett. 508 (2): 215–220. doi:10.1016/s0014-5793(01)03045-9. PMID 11718718.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Wang, J., Liu, Y., Cai, Y., Zhang, F., Xia, G. and Xiang, F. (2010). "Cloning and functional analysis of geraniol 10-hydroxylase, a cytochrome P450 from Swertia mussotii Franch". Biosci. Biotechnol. Biochem. 74 (8): 1583–1590. doi:10.1271/bbb.100175. PMID 20699579.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Sung, P.H., Huang, F.C., Do, Y.Y. and Huang, P.L. (2011). "Functional expression of geraniol 10-hydroxylase reveals its dual function in the biosynthesis of terpenoid and phenylpropanoid". J. Agric. Food Chem. 59 (9): 4637–4643. doi:10.1021/jf200259n. PMID 21504162.
{{cite journal}}: CS1 maint: multiple names: authors list (link)
External links
- Geraniol+8-hydroxylase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)