Gertrude Erika Perlmann (April 20, 1912 – September 9, 1974) was a Czechoslovakian-born U.S. biochemist. She is known for her work in protein chemistry, particularly her work with phosphoproteins and the structure and action of pepsin and pepsinogen. 
She earned a doctorate in chemistry and physics at the German University of Prague in 1936. She fled Nazi occupation of Czechoslovakia for Denmark in 1936. She worked at the Carlsberg Laboratory in Copenhagen until 1939.
At the beginning of World War II, she emigrated to the United States. She began work in the laboratories of Harvard Medical School and then at Massachusetts General Hospital in Boston, Massachusetts. She moved in 1945 to New York City, where she worked as a visiting investigator at the Rockefeller Institute. 
In the 1960s she was awarded the silver medal of the Chemical Society and the Legion of Honor by the French. She was one of the first female corresponding members of the Académie des Sciences. She won the Garvan–Olin Medal for women in chemistry in 1965 from the American Chemical Society. She was also awarded the French Order of Merit in 1974. 
- Shearer, Benjamin F.; Barbara S. Shearer (1997). Notable Women in the Physical Sciences A Biological Dictionary. Westport, CT: Greenwood Publishing Group, Inc. pp. 301–305. ISBN 0-313-29303-1.
- Ogilvie, Marilyn; Joy Harvey (2000). The Biographical Dictionary of Women in Science. New York and London: Routledge. pp. 1007–1008. ISBN 0-415-92038-8.
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