In 1990, producers Phil Wilde and Jean-Paul de Coster had previously gained success with AB Logic, and were looking for another vehicle for their songs. 2 Unlimited formed when Wilde and DeCoster were introduced to rapper Ray Slijngaard and vocalist Anita Doth by Marvin D., who had featured both in his rap group in the past.
"Get Ready for This" was released in September 1991 as the lead single from 2 Unlimited's debut album Get Ready! Originally, the single was produced as an instrumental, titled the "Orchestral Mix". Conscious of their popularity, Wilde & De Coster wanted a more accessible, formatted formula for their project to grow. Ray was then asked to write lyrics and add a rap to the track. On Ray's suggestion, Anita joined as the female vocalist.
The rap version was released with raps by Ray Slijngaard and vocals by Anita Doth. For the UK release of the single, an edit of the original "Orchestral Mix" was used, without vocals except for the line "Y'all ready for this?" This was sampled from The D.O.C.'s hit single "It's Funky Enough." This was done by record producer Pete Waterman, who owned the record label 2 Unlimited were licensed to for UK releases.
"Get Ready for This" was an immediate success throughout Europe with notable peaks worldwide, including Australia and the U.S. It is arguably the most famous of the band's singles in the United States having charted at no. 14 on the US BillboardHot Dance Club Play chart, no. 17 on the Top 40 Mainstream and no. 38 on the Billboard Hot 100, making it the band's only Top 40 hit in the U.S.
After the moderate success of the 2 Unlimited compilation album Greatest Hits Remixes in 2001, two white labels were released with remixes of "Get Ready for This". The first 12" was released in May 2001 in Belgium with a remix by DJ/producer Yves Deruyter. Although just a single sided pressing featuring the full 12" remix, the radio edit was officially released later in the 2002 release Trance Remixes (Special Edition).
In 2013, American DJ/producer Steve Aoki released a remix of "Get Ready for This" on Byte Records as part of a forthcoming 2 Unlimited greatest hits album. The Rap and Orchestral mixes featured on the original "Get Ready for This" single were also included.