General elections were held in Ghana on 7 December 2000, with a second round of the presidential election on 28 December.
In the presidential election, John Kufuor of the New Patriotic Party (NPP) led the field in the first round of voting, taking 48 percent of the vote. Vice President John Atta Mills of the National Democratic Congress (NDC) finished second, with 44 percent. Kufuor defeated Atta-Mills in the second round with 57 percent of the vote. The NPP also won the most seats in the parliamentary elections, ending eight years of NDC dominance. However, with 99 of the 200 seats, it was two seats short of a majority.