|Chemical and physical data|
|Molar mass||146.5 kg/mol|
|(what is this?)|
Girentuximab (trade name Rencarex) is a chimeric IgG1 monoclonal antibody to carbonic anhydrase IX (CAIX). CAIX is expressed on the surface of most renal cancer cells and is hypothesized to be on the surface of other tumor cells. It is investigational agent in clinical trials for renal cell carcinoma. Its development was suspended during phase III trials due to efficacy.
- "Statement On A Nonproprietary Name Adopted By The USAN Council: Girentuximab" (PDF). American Medical Association.
- Bedke J, Stenzl A (2013). "Immunotherapeutic strategies for the treatment of renal cell carcinoma: where are we now?". Expert Review of Anticancer Therapy. 13 (12): 1399–408. PMID 24215158. doi:10.1586/14737140.2013.856761.
- Girentuximab (Rencarex) for renal cell carcinoma
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