Regondi was born of a German mother and an Italian father in Geneva, Switzerland. A child prodigy, Fernando Sor dedicated his Souvenir d'amitié op. 46 to Regondi in 1831, when the boy was just nine.
There is a reference to his appearing in London in 1831, presented as a child prodigy of the guitar. Most of Regondi's concertina music was written for the English system, however, at which he was a virtuoso, though his guitar music is probably better known. His works for solo guitar comprise a set of etudes and five larger works.
^The Times, 16 June 1831; p. 3; "A NEW MUSICAL FUND: […] An interesting little boy of the name of Regondi, apparently between six and seven years of age, performed a fantasia on the guitar, with most manly power and surprising brilliancy. He was seated on a stool, which was placed on the pianoforte […].”
^The Times, 26 April 1837; p. 5; "GREAT CONCERT-ROOM – KING'S THEATRE […] There was also a novelty in the shape of an instrument called 'a concertina,' an improvement on the accordion, which has been such a favourite musical toy for the last two or three years. The tones of this instrument are sweet and pleasing; but far more striking than the concertina itself were the feeling and ease with which it was played by that clever little boy Giulio Regondi, who executed several intricate passages with surprising facility and precision."