Glabellar reflex

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Glabellar reflex (also known as the "glabellar tap sign") (Glabella) is a primitive reflex. It is elicited by repetitive tapping on the forehead. Subjects blink in response to the first several taps. If the blinking persists, this is known as Myerson's sign and is abnormal and a sign of frontal release; it is often seen in people who have Parkinson's disease.[1]

The afferent sensory signals are transmitted by the trigeminal nerve, and the efferent signals come back to orbicularis oculi muscle via the facial nerve, which in turn reflexively contracts causing blinking.

See also[edit]


  1. ^ "Glabellar tap". GP Notebook. Retrieved 18 April 2012. 


  • Ritz, Beate; Rhodes, Shannon L.; Bordelon, Yvette; Bronstein, Jeff; Lewis, Patrick (May 15, 2012). "α-Synuclein Genetic Variants Predict Faster Motor Symptom Progression in Idiopathic Parkinson Disease". PLoS ONE 7 (5): e36199. doi:10.1371/journal.pone.0036199. 
  • Pishvaee, Babak; Payne, Gregory S.; Costaguta, Giancarlo; Yeung, Bonny G.; Ryazantsev, Sergey; Greener, Tsvika; Greene, Lois E.; Eisenberg, Evan; McCaffery, J. Michael (14 November 2000). Nature Cell Biology 2 (12): 958–963. doi:10.1038/35046619.  Missing or empty |title= (help)
  • Paisán-Ruiz, Coro; Guevara, Rocio; Federoff, Monica; Hanagasi, Hasmet; Sina, Fardaz; Elahi, Elahe; Schneider, Susanne A.; Schwingenschuh, Petra; Bajaj, Nin; Emre, Murat; Singleton, Andrew B.; Hardy, John; Bhatia, Kailash P.; Brandner, Sebastian; Lees, Andrew J.; Houlden, Henry (15 September 2010). "Early-onset L-dopa-responsive parkinsonism with pyramidal signs due to ATP13A2, PLA2G6, FBXO7 and spatacsin mutations". Movement Disorders 25 (12): 1791–1800. doi:10.1002/mds.23221. 
  • Edvardson, Simon; Cinnamon, Yuval; Ta-Shma, Asaf; Shaag, Avraham; Yim, Yang-In; Zenvirt, Shamir; Jalas, Chaim; Lesage, Suzanne; Brice, Alexis; Taraboulos, Albert; Kaestner, Klaus H.; Greene, Lois E.; Elpeleg, Orly; Wider, Christian (May 1, 2012). "A Deleterious Mutation in DNAJC6 Encoding the Neuronal-Specific Clathrin-Uncoating Co-Chaperone Auxilin, Is Associated with Juvenile Parkinsonism". PLoS ONE 7 (5): e36458. doi:10.1371/journal.pone.0036458.