Glicaramide

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Glicaramide
Glicaramide.svg
Clinical data
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
Formula C30H42N6O5S
Molar mass 598.7567 g/mol

Glicaramide (SQ-65993) is an orally bioavailable anti-diabetic medication.[1] It has a similar potency as glibenclamide (glyburide) in the class of medication known as sulfonylureas. Its structure is similar since it has a cyclic acyl group which replaces the latter's 2-methoxy-5-chlorobenzyl.[2] Same as glibenclamide, it is classified as a second-generation sulfonylurea. It may have more pronounced extra-pancreatic effects than glibenclamide or tolbutamide.[3]

See also[edit]

References[edit]

  1. ^ Hoehn, H.; Polacek, I.; Schulze, E. (1973). "Potential antidiabetic agents. Pyrazolo[3,4-b]pyridines". Journal of Medicinal Chemistry. 16 (12): 1340–1346. PMID 4358224. doi:10.1021/jm00270a006. 
  2. ^ Progress in Medicinal Chemistry, Volume 18 (v. 18) (Hardcover). Elsevier Science. 1981. ISBN 0-444-80345-9. 
  3. ^ West, G.B. (Jan 1, 1981). Ellis, GP, ed. Progress in medicinal chemistry. Amsterdam: Elsevier. p. 202. ISBN 9780444803450.