Gliquidone

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Gliquidone
Gliquidone.svg
Clinical data
Trade names Glurenorm
AHFS/Drugs.com International Drug Names
Pregnancy
category
  • C
Routes of
administration
Oral (tablets)
ATC code
Legal status
Legal status
  • UK: POM (Prescription only)
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability High (Tmax = 2–3 hours)
Metabolism Extensive hepatic
Onset of action 1–1.5 hours
Excretion Biliary (95%), renal (5%)
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
ECHA InfoCard 100.046.770
Chemical and physical data
Formula C27H33N3O6S
Molar mass 527.634 g/mol
3D model (Jmol)
  (verify)

Gliquidone (INN, sold under the trade name Glurenorm) is an anti-diabetic medication in the sulfonylurea class. It is classified as a second-generation sulfonylurea. It is used in the treatment of diabetes mellitus type 2. It is marketed by the pharmaceutical company Boehringer Ingelheim (Germany).

Contraindications[edit]

Pharmacokinetics[edit]

Gliquidone is fully metabolized by the liver. Its metabolites are excreted virtually completely with bile (even with long-term administration), thus allowing the use of medication in diabetic patients suffering from kidney disease and diabetic nephropathy.[1]

References[edit]

  1. ^ a b "Glurenorm (gliquidone) 30 mg Tablets, for Oral Use. Full Prescribing Information". Russian State Register of Medicinal Products (in Russian). Boehringer Ingelheim. Retrieved 12 July 2016.