Glucosamine-6-phosphate deaminase hexamer, Human
|PDB structures||RCSB PDB PDBe PDBsum|
|Gene Ontology||AmiGO / QuickGO|
- D-glucosamine 6-phosphate + H2O D-fructose 6-phosphate + NH3
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in compounds that have not been otherwise categorized within EC number 3.5. The systematic name of this enzyme class is 2-amino-2-deoxy-D-glucose-6-phosphate aminohydrolase (ketol isomerizing). Other names in common use include glucosaminephosphate isomerase, glucosamine-6-phosphate isomerase, phosphoglucosaminisomerase, glucosamine phosphate deaminase, aminodeoxyglucosephosphate isomerase, and phosphoglucosamine isomerase. This enzyme participates in aminosugars metabolism. This enzyme has at least one effector, N-Acetyl-D-glucosamine 6-phosphate.
- COMB DG, ROSEMAN S (1958). "Glucosamine metabolism. IV. Glucosamine-6-phosphate deaminase". J. Biol. Chem. 232 (2): 807–27. PMID 13549465.
- Pattabiraman TN, Bachhawat BK (1961). "Purification of glucosamine 6-phosphate deaminase from human brain". Biochim. Biophys. Acta. 54 (2): 273–283. doi:10.1016/0006-3002(61)90366-3. PMID 14484386.
- Wolfe JB, Britton BB, Nakada HI (1957). "Glucosamine degradation by Escherichia coli. III. Isolation and studies of "phosphoglucosaminisomerase"". Arch. Biochem. Biophys. 66 (2): 333–339. doi:10.1016/S0003-9861(57)80008-3.
|This EC 3.5 enzyme-related article is a stub. You can help Wikipedia by expanding it.|