Glucose-1-phosphate phosphodismutase

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glucose-1-phosphate phosphodismutase
Identifiers
EC number2.7.1.41
CAS number9026-25-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a glucose-1-phosphate phosphodismutase (EC 2.7.1.41) is an enzyme that catalyzes the chemical reaction

2 D-glucose 1-phosphate ⇌ D-glucose + D-glucose 1,6-bisphosphate

Hence, this enzyme has one substrate, D-glucose 1-phosphate, and two products, D-glucose and D-glucose 1,6-bisphosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is D-glucose-1-phosphate:D-glucose-1-phosphate 6-phosphotransferase. This enzyme participates in glycolysis / gluconeogenesis and starch and sucrose metabolism.

References[edit]

  • LELOIR LF, TRUCCO RE, et al. (1949). "The formation of glucose diphosphate by Escherichia coli". Arch. Biochem. 24 (1): 65–74. PMID 15400363.
  • Sidbury JB, Rosenberg LL, Najjar VA (1956). "Muscle glucose-1-phosphate transphosphorylase". J. Biol. Chem. 222 (1): 89–96. PMID 13366982.