Glutamate dehydrogenase (NAD(P)+)

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Glutamate dehydrogenase (NAD(P)+)
1l1f.jpg
glutamate dehydrogenase hexamer, Human
Identifiers
EC number1.4.1.3
CAS number2604152
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Glutamate dehydrogenase (NAD(P)+) (EC 1.4.1.3, glutamic dehydrogenase, glutamate dehydrogenase [NAD(P)+]) is an enzyme with systematic name L-glutamate:NAD(P)+ oxidoreductase (deaminating).[1][2][3] This enzyme catalyses the following chemical reaction

L-glutamate + H2O + NAD(P)+ 2-oxoglutarate + NH4+ + NAD(P)H + H+

References[edit]

  1. ^ Olson, J.A.; Anfinsen, C.B. (1952). "The crystallization and characterization of L-glutamic acid dehydrogenase". J. Biol. Chem. 197: 67–79. PMID 12981035.
  2. ^ Smith, E.L.; Austen, B.M.; Blumenthal, K.M.; Nyc, J.F. (1975). "Glutamate dehydrogenases". In Boyer, P.D. The Enzymes. 11 (3rd ed.). New York: Academic Press. pp. 293–367.
  3. ^ Strecker, H.J. (1953). "Glutamic dehydrogenase". Arch. Biochem. Biophys. 46: 128–140. doi:10.1016/0003-9861(53)90176-3. PMID 13092953.

External links[edit]