Glutamate dehydrogenase (NAD(P)+)

From Wikipedia, the free encyclopedia
Glutamate dehydrogenase (NAD(P)+)
1l1f.jpg
glutamate dehydrogenase hexamer, Human
Identifiers
EC no.1.4.1.3
CAS no.2604152
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

Glutamate dehydrogenase (NAD(P)+) (EC 1.4.1.3, glutamic dehydrogenase, glutamate dehydrogenase [NAD(P)+]) is an enzyme with systematic name L-glutamate:NAD(P)+ oxidoreductase (deaminating).[1][2][3] This enzyme catalyses the following chemical reaction

L-glutamate + H2O + NAD(P)+ 2-oxoglutarate + NH4+ + NAD(P)H + H+

References[edit]

  1. ^ Olson JA, Anfinsen CB (May 1952). "The crystallization and characterization of L-glutamic acid dehydrogenase". The Journal of Biological Chemistry. 197 (1): 67–79. PMID 12981035.
  2. ^ Smith, E.L.; Austen, B.M.; Blumenthal, K.M.; Nyc, J.F. (1975). "Glutamate dehydrogenases". In Boyer, P.D. (ed.). The Enzymes. Vol. 11 (3rd ed.). New York: Academic Press. pp. 293–367.
  3. ^ Strecker HJ (September 1953). "Glutamic dehydrogenase". Archives of Biochemistry and Biophysics. 46 (1): 128–40. doi:10.1016/0003-9861(53)90176-3. PMID 13092953.

External links[edit]