Glycine oxidase

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Glycine oxidase
4ysh.jpg
Glycine oxidase tetramer, Geobacillus kaustophilus
Identifiers
EC number1.4.3.19
CAS number39307-16-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Glycine oxidase (EC 1.4.3.19) is an enzyme with systematic name glycine:oxygen oxidoreductase (deaminating).[1][2] This enzyme catalyses the following chemical reaction

glycine + H2O + O2 glyoxylate + NH3 + H2O2 (overall reaction)
(1a) glycine + O2 2-iminoacetate + H2O2
(1b) 2-iminoacetate + H2O glyoxylate + NH3

This flavoenzyme containing non-covalently bound FAD.

References[edit]

  1. ^ Job, V.; Marcone, G.L.; Pilone, M.S.; Pollegioni, L. (2002). "Glycine oxidase from Bacillus subtilis. Characterization of a new flavoprotein". J. Biol. Chem. 277 (9): 6985–6993. doi:10.1074/jbc.M111095200. PMID 11744710.
  2. ^ Nishiya, Y.; Imanaka, T. (1998). "Purification and characterization of a novel glycine oxidase from Bacillus subtilis". FEBS Lett. 438 (3): 263–266. doi:10.1016/s0014-5793(98)01313-1. PMID 9827558.

External links[edit]