Goldstein's toe sign

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"Goldstein's Toe Sign" is a feature identified by Dr. Hyman Isaac Goldstein (1887–1954), an American physician and medical historian. A greater distance separates the largest two toes of some people exhibiting Down syndrome or cretinism."[1]

References[edit]

Wide distance between the great toe and the adjoining toe; associated with cretinism and trisomy 21.