Granuloma multiforme

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Granuloma multiforme
Classification and external resources
Specialty dermatology
ICD-10 L92.8 (ILDS L92.840)

Granuloma multiforme (also known as "Mkar disease" and "granuloma multiforme (Leiker)")[1] is a cutaneous condition most commonly seen in central Africa, and rarely elsewhere, characterized by skin lesions that are on the upper trunk and arms in sun-exposed areas.[2]:707 It may be confused with tuberculoid leprosy, with which it has clinical similarities. The condition was first noted by Gosset in the 1940s, but it was not until 1964 that Leiker coined the term to describe "a disease resembling leprosy" in his study in Nigeria.[3]

See also[edit]


  1. ^ Meyers, Wayne; Connor, DH; Shannon, R (January 1970). "Histologic characteristics of granuloma multiforme (Mkar disease). Including a comparison with leprosy and granuloma annulare. Report of first case from Congo (Kinshasa)". International Journal of Leprosy and Other Mycobacterial Diseases. 38 (3): 241–249. 
  2. ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0. 
  3. ^ Kumari, Rashmi; Devinder Mohan, Thappa; Chougule, Abhijit; Adityan, Balaji (2009). "Granuloma multiforme: A report from India". Indian Journal of Dermatology, Venereology and Leprology. 75 (3): 296–299.