Meyer was born in Grand Rapids, MI to parents Rita and Jay. He has one older sibling, Matthew Meyer. He met and married fellow runner Paula Lettis in 1980  while living in Boston and together they had three children, Nicolle (1981), Jacob (1983) and Daniel (1986). He divorced in 2005 while living in Dexter, MI.
Meyer resides near Rockford, MI, and since 2008 has served as Associate Vice President for Institutional Advancement at Aquinas College. Previously, Greg was employed from approximately 2000 through March 2007 by the University of Michigan as director of Major Gifts for the Greater Michigan Region, where he helped raise over $125 million for the university.