Lee was born to Korean immigrants in Los Angeles, where she grew up as well. While attending Harvard-Westlake School she became interested in the performing arts. After high school she went on pursuing that interest and studied communication and theater at Northwestern University. Then she moved to New York City to work as an actress.
She has played Soojin in Girls and Homeless Heidi in High Maintenance. She was a guest star in the TV shows New Girl and Wayward Pines. She costarred as Hae Won in Sisters alongside Tina Fey and Amy Poehler. Lee starred as Maxine in the Netflix comedy-drama series Russian Doll.
|2006||Law & Order: Special Victims Unit||Heather Kim||Episode: "Taboo"|
|2006||The Electric Company||Greta||Episode: "Pilot"|
|2012–2013||High Maintenance||Heidi||2 episodes|
|2012–2013||Nurse Jackie||Nurse||3 episodes|
|2013||Royal Pains||Daisy||Episode: "Pins and Needles"|
|2013||Bad Management||Mel||TV Movie|
|2013–2016||Inside Amy Schumer||Herself||Recurring|
|2014||Seriously Distracted||Paige||Main cast|
|2014||Old Soul||Alix||TV Pilot|
|2014–2015||New Girl||Kai||5 episodes|
|2014–2015||Above Average Presents||Various||2 episodes|
|2015||Good at Life||Dr. Simon||TV Pilot|
|2015||Sharing||Heidi Salazar||TV Pilot|
|2016–2018||High Maintenance||Heidi||2 episodes|
|2017||Broad City||Dr. Elizabeth Fuller||Episode: "Witches"|
|2017–2018||The Good Fight||Amber Wood-Lutz||2 episodes|
|2019–present||Russian Doll||Maxine||Main cast|
|2019||The Other Two||Genevieve Kim||Episode: "Chase Shoots a Music Video"|
|2012||Hello I Must Be Going||Gap Girl|
|2013||Hair Brained||Gertrude Lee|
|2014||St. Vincent||Teller #23|
|2014||While We're Young||Sundance Interviewer (voice)|
|2014||Top Five||Pill Girl|
|2016||10 Crosby||Cabbie||Short film; segment: "HiFi"|
|2016||Money Monster||Amy Lee|
|2017||Fits and Starts||Jennifer|
|2017||Cabiria, Charity, Chastity||Nina the Showgirl||Short film|
|2018||In a Relationship||Maggie|
|2018||Spider-Man: Into the Spider-Verse||Interesting Person #2|
- Cara Buckley: Greta Lee On Hollywood Stereotypes and Playing the ‘Lovable Weirdo’. The New York Times, 2015-12-17
- "Greta Lee". Aritzia.com (archived version). Archived from the original on April 2, 2015.
- Tae Hong: ‘Too American’ no more: Greta Lee just may be Hollywood’s new comedy ‘It’ girl. The Korean Times, 2014-12-17
- "Greta Lee Interview". ELLE. 2014-05-22.
- Bradley, Laura (February 7, 2019). "Russian Doll's Greta Lee Breaks Down That Crazy Party, Maxine's Bold Look". Vanity Fair. Retrieved February 14, 2019.