Guanidinoacetate kinase

From Wikipedia, the free encyclopedia
Jump to: navigation, search
guanidinoacetate kinase
Identifiers
EC number 2.7.3.1
CAS number 9026-60-2
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a guanidinoacetate kinase (EC 2.7.3.1) is an enzyme that catalyzes the chemical reaction

ATP + guanidinoacetate \rightleftharpoons ADP + phosphoguanidinoacetate

Thus, the two substrates of this enzyme are ATP and guanidinoacetate, whereas its two products are ADP and phosphoguanidinoacetate.

Guanidinoacetate kinase belongs to the family of transferases, specifically those that transfer phosphorus-containing groups (phosphotransferases) with a nitrogenous group as acceptor. The systematic name of this enzyme class is ATP:guanidinoacetate N-phosphotransferase. This enzyme is also called glycocyamine kinase. This enzyme participates in arginine and proline metabolism.

References[edit]

  • HOBSON GE, REES KR (1957). "The annelid phosphokinases". Biochem. J. 65 (2): 305–7. PMC 1199870. PMID 13403909. 
  • Pradel LA, Kassab R, Conlay C, Nguyen Van Thoai (1968). "[Properties and amino acid composition of purified ATP: guanidinoacetate phosphotransferase]". Biochim. Biophys. Acta. 154 (2): 305–14. PMID 5637051. 
  • Pradel L-A, Kassab R and Thoai NV (1964). "Sur l'acide adenosine-triphosphorique:guanidoacetate phosphotransferase". Biochim. Biophys. Acta 81: 86–95. doi:10.1016/0926-6569(64)90338-4. 
  • Thoai NV (1957). "Sur la taurocyamine et la glycocyamine phosphokinase". Bull. Soc. Chim. Biol. 39: 197–208.