Guanosine diphosphate

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Guanosine diphosphate
Skeletal formula of guanosine diphosphate
Space-filling model of the guanosine diphosphate anion
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
Properties
C10H15N5O11P2
Molar mass 443.200522
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Guanosine diphosphate, abbreviated GDP, is a nucleoside diphosphate. It is an ester of pyrophosphoric acid with the nucleoside guanosine. GDP consists of a pyrophosphate group, a pentose sugar ribose, and the nucleobase guanine.[1]

GDP is the product of GTP dephosphorylation by GTPases, e.g., the G-proteins that are involved in signal transduction.

GDP is converted into GTP with the help of pyruvate kinase and phosphoenolpyruvate.

See also[edit]

References[edit]

  1. ^ Crane, Laura J; Miller, David Lee (1974). "Guanosine triphosphate and guanosine diphosphate as conformation-determining molecules. Differential interaction of a fluorescent probe with the guanosine nucleotide complexes of bacterial elongation factor Tu". Biochemistry. 13 (5): 933–939. doi:10.1021/bi00702a017.