Guanylate cyclase activator

From Wikipedia, the free encyclopedia
Jump to: navigation, search

A guanylate cyclase activator (or "GUCA") is one of group of proteins which upregulates guanylate cyclase. It is also known as guanylate cyclase-activating protein, with the abbreviation "GCAP". Mutations can be associated with vision defects.[1]

There are five genes involved:


  1. ^ Payne AM, Downes SM, Bessant DA, et al. (1998). "A mutation in guanylate cyclase activator 1A (GUCA1A) in an autosomal dominant cone dystrophy pedigree mapping to a new locus on chromosome 6p21.1". Hum. Mol. Genet. 7 (2): 273–7. PMID 9425234. doi:10.1093/hmg/7.2.273. 

External links[edit]