Guvacoline

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Guvacoline
Guvacoline.png
Names
Preferred IUPAC name
Methyl 1,2,5,6-tetrahydropyridine-3-carboxylate
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
KEGG
UNII
  • InChI=1S/C7H11NO2/c1-10-7(9)6-3-2-4-8-5-6/h3,8H,2,4-5H2,1H3
    Key: DYPLDWLIOGXSSE-UHFFFAOYSA-N
  • COC(=O)C1=CCCNC1
Properties
C7H11NO2
Molar mass 141.170 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Guvacoline is a compound with the chemical formula C7H11NO2.[1] It is a component of Areca nut and a precursor of guvacine. It agonizes musacarinic receptors just like arecoline but unlike arecoline it lacks nicotinic activity.[2]

See also[edit]

References[edit]

  1. ^ PubChem. "Guvacoline". pubchem.ncbi.nlm.nih.gov. Retrieved 2020-06-14.
  2. ^ Horenstein NA, Quadri M, Stokes C, Shoaib M, Papke RL (May 2019). "Cracking the Betel Nut: Cholinergic Activity of Areca Alkaloids and Related Compounds". Nicotine & Tobacco Research. 21 (6): 805–812. doi:10.1093/ntr/ntx187. PMC 6528145. PMID 29059390.