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Available structures
PDB Ortholog search: PDBe RCSB
Aliases H1FX, H1X, H1.10, H1 histone family member X
External IDs MGI: 2685307 HomoloGene: 4397 GeneCards: H1FX
Gene location (Human)
Chromosome 3 (human)
Chr. Chromosome 3 (human)[1]
Chromosome 3 (human)
Genomic location for H1FX
Genomic location for H1FX
Band 3q21.3 Start 129,314,771 bp[1]
End 129,316,277 bp[1]
RNA expression pattern
PBB GE H1FX 204805 s at fs.png
More reference expression data
Species Human Mouse
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC) Chr 3: 129.31 – 129.32 Mb Chr 6: 87.98 – 87.98 Mb
PubMed search [3] [4]
View/Edit Human View/Edit Mouse

Histone H1x is a protein that in humans is encoded by the H1FX gene.[5][6][7]

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H1 family.[7]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000184897 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000044927 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Yamamoto T, Horikoshi M (Dec 1996). "Cloning of the cDNA encoding a novel subtype of histone H1". Gene. 173 (2): 281–285. doi:10.1016/0378-1119(96)00020-0. PMID 8964515. 
  6. ^ Albig W, Doenecke D (Feb 1998). "The human histone gene cluster at the D6S105 locus". Hum Genet. 101 (3): 284–294. doi:10.1007/s004390050630. PMID 9439656. 
  7. ^ a b "Entrez Gene: H1FX H1 histone family, member X". 

Further reading[edit]