H2AFB3

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H2AFB3
Identifiers
Aliases H2AFB3, H2ABBD, H2AFB, H2A histone family member B3
External IDs MGI: 3642445 HomoloGene: 129517 GeneCards: H2AFB3
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_080720

NM_001102665

RefSeq (protein)

NP_001017991
NP_542451

NP_001096135

Location (UCSC) Chr X: 155.46 – 155.46 Mb Chr X: 117.01 – 117.02 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

H2A histone family, member B3 is a protein that in humans is encoded by the H2AFB3 gene.[3]

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. This gene is part of a region that is repeated three times on chromosome X, once in intron 22 of the F8 gene and twice closer to the Xq telomere. This record represents the most telomeric copy. [provided by RefSeq, Jul 2008].[3]

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