H2AFJ

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H2AFJ
Protein H2AFJ PDB 1aoi.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases H2AFJ, H2AJ, H2A histone family member J
External IDs MGI: 3606192 HomoloGene: 128575 GeneCards: 55766
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_018267
NM_177925

NM_177688

RefSeq (protein)

NP_808760.1

NP_808356.1

Location (UCSC) Chr 12: 14.77 – 14.78 Mb Chr 6: 136.81 – 136.81 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Histone H2A.J is a protein that in humans is encoded by the H2AFJ gene.[1]

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is located on chromosome 12 and encodes a variant H2A histone. The protein is divergent at the C-terminus compared to the consensus H2A histone family member.[1]

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