HBQ1

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HBQ1
Identifiers
Aliases HBQ1, HBQ, hemoglobin subunit theta 1
External IDs MGI: 3613460 HomoloGene: 3895 GeneCards: 3049
RNA expression pattern
PBB GE HBQ1 220807 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005331

NM_001033981

RefSeq (protein)

NP_005322.1

n/a

Location (UCSC) Chr 16: 0.18 – 0.18 Mb Chr 11: 32.29 – 32.29 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Hemoglobin subunit theta-1 is a protein that in humans is encoded by the HBQ1 gene.[1][2]

Theta-globin mRNA is found in human fetal erythroid tissue but not in adult erythroid or other nonerythroid tissue. The theta-1 gene may be expressed very early in embryonic life, perhaps sometime before 5 weeks. Theta-1 is a member of the human alpha-globin gene cluster that involves five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta-1 - 3'. Research supports a transcriptionally active role for the gene and a functional role for the peptide in specific cells, possibly those of early erythroid tissue.[2]

References[edit]

  1. ^ Higgs DR, Vickers MA, Wilkie AO, Pretorius IM, Jarman AP, Weatherall DJ (May 1989). "A review of the molecular genetics of the human alpha-globin gene cluster". Blood 73 (5): 1081–104. PMID 2649166. 
  2. ^ a b "Entrez Gene: HBQ1 hemoglobin, theta 1". 

Further reading[edit]