HBXIP

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LAMTOR5
Protein HBXIP PDB 3MS6.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases LAMTOR5, HBXIP, XIP, late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
External IDs MGI: 1915826 HomoloGene: 4668 GeneCards: LAMTOR5
RNA expression pattern
PBB GE HBXIP 202299 s at fs.png

PBB GE HBXIP 202300 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006402

NM_026774

RefSeq (protein)

NP_006393
NP_006393.2

NP_081050.2
NP_081050

Location (UCSC) Chr 1: 110.4 – 110.41 Mb Chr 3: 107.28 – 107.28 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Hepatitis B virus X-interacting protein is a protein that in humans is encoded by the HBXIP gene.[3][4]

This gene encodes a protein that specifically complexes with the C-terminus of hepatitis B virus X protein (HBx). The function of this protein is to negatively regulate HBx activity and thus to alter the replication life cycle of the virus.[4]

Interactions[edit]

HBXIP has been shown to interact with NCOA6.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Melegari M, Scaglioni PP, Wands JR (Mar 1998). "Cloning and Characterization of a Novel Hepatitis B Virus x Binding Protein That Inhibits Viral Replication". J Virol. 72 (3): 1737–43. PMC 109461Freely accessible. PMID 9499022. 
  4. ^ a b "Entrez Gene: HBXIP hepatitis B virus x interacting protein". 
  5. ^ Kong, Hee Jeong; Park Min Jung; Hong SunHwa; Yu Hyun Jung; Lee Young Chul; Choi Young Hyun; Cheong JaeHun (Nov 2003). "Hepatitis B virus X protein regulates transactivation activity and protein stability of the cancer-amplified transcription coactivator ASC-2". Hepatology. United States. 38 (5): 1258–66. doi:10.1053/jhep.2003.50451. ISSN 0270-9139. PMID 14578865. 

Further reading[edit]