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HDL may refer to one of the following:
- Hardware description language
- Handle System identifier (Hdl.handle.net)
- High-density lipoprotein, so-called "good cholesterol"
- Les Hurlements d'Léo, an alternative rock band from France
- GE HDL diesel engine
- Huey, Dewey, and Louie, Disney-characters, nephews of Donald Duck
- HDL System, HDL Universal Tactical role-playing game system produced by Tremorworks, LLC
- Huntington's disease-like syndromes, a family of genetic neurological diseases
| disambiguation page lists articles associated with the title HDL.
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