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HFM1 is a gene that in humans encodes a protein necessary for homologous recombination of chromosomes.[1] Biallelic mutations in HFM1 cause recessive primary ovarian insufficiency.[1]


  1. ^ a b Wang, Jian; Zhang, Wenxiang; Jiang, Hong; Wu, Bai-Lin (2014). "Mutations inHFM1in Recessive Primary Ovarian Insufficiency". New England Journal of Medicine. 370 (10): 972–974. doi:10.1056/NEJMc1310150. ISSN 0028-4793.