HFM1

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HFM1
Identifiers
AliasesHFM1, MER3, POF9, SEC63D1, Si-11, Si-11-6, helicase, ATP-dependent DNA helicase homolog, ATP dependent DNA helicase homolog
External IDsMGI: 3036246 HomoloGene: 87103 GeneCards: HFM1
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for HFM1
Genomic location for HFM1
Band1p22.2Start91,260,766 bp[1]
End91,404,869 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001017975

NM_001252516
NM_177873

RefSeq (protein)

NP_001017975

NP_001239445
NP_808541

Location (UCSC)Chr 1: 91.26 – 91.4 MbChr 5: 106.84 – 106.93 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

HFM1 is a gene that in humans encodes a protein necessary for homologous recombination of chromosomes.[5] Biallelic mutations in HFM1 cause recessive primary ovarian insufficiency.[5]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000162669 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000043410 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ a b Wang J, Zhang W, Jiang H, Wu BL (March 2014). "Mutations in HFM1 in recessive primary ovarian insufficiency". The New England Journal of Medicine. 370 (10): 972–4. doi:10.1056/NEJMc1310150. PMID 24597873.