HHIP

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HHIP
Protein HHIP PDB 2WFT.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases HHIP, HIP, hedgehog interacting protein
External IDs MGI: 1341847 HomoloGene: 32469 GeneCards: 64399
RNA expression pattern
PBB GE HHIP gnf1h05971 at tn.png

PBB GE HHIP gnf1h05972 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_022475

NM_020259

RefSeq (protein)

NP_071920.1

NP_064655.4

Location (UCSC) Chr 4: 144.65 – 144.75 Mb Chr 8: 79.97 – 80.06 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Hedgehog interacting protein is a protein that in humans is encoded by the HHIP gene.[3][4][5]

This gene encodes a protein similar to the mouse hedgehog interacting protein, a regulatory component of the Hedgehog signaling pathway. Members of the hedgehog family are evolutionarily conserved proteins which are involved in many fundamental processes in embryonic development, including anteroposterior patterns of limbs and regulation of left-right asymmetry.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Bak M, Hansen C, Friis Henriksen K, Tommerup N (Jul 2001). "The human hedgehog-interacting protein gene: structure and chromosome mapping to 4q31.21→q31.3". Cytogenet Cell Genet. 92 (3–4): 300–3. doi:10.1159/000056918. PMID 11435703. 
  4. ^ Ingham PW, McMahon AP (Dec 2001). "Hedgehog signaling in animal development: paradigms and principles". Genes Dev. 15 (23): 3059–87. doi:10.1101/gad.938601. PMID 11731473. 
  5. ^ a b "Entrez Gene: HHIP hedgehog interacting protein". 

Further reading[edit]