HIST1H4J

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HIST1H4J
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases HIST1H4J, H4/e, H4F2iv, H4FE, dJ160A22.2, histone cluster 1, H4j, histone cluster 1 H4 family member j
External IDs MGI: 2448425 HomoloGene: 134492 GeneCards: HIST1H4J
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_021968

NM_175655

RefSeq (protein)
Location (UCSC) Chr 6: 27.82 – 27.82 Mb Chr 13: 23.55 – 23.55 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Histone cluster 1, H4j is a protein that in humans is encoded by the HIST1H4J gene.[3]

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Jul 2008].[3]

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